Fibronectin anticorps

N° du produit ABIN1107236

L’anticorps Souris Monoclonal anti-Fibronectin a été validé pour WB, EIA et IHC (fro). Il convient pour détecter Fibronectin dans des échantillons de Humain, Rat, Poulet, Lapin et Cobaye.

Aperçu rapide pour Fibronectin anticorps (ABIN1107236)

Antigène: Fibronectin

Reactivité: Humain, Rat, Poulet, Lapin, Cobaye

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Fibronectin est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: DH1

Détail du produit anti-Fibronectin anticorps

Specificité: The antibody is specific to extradomain A (EDA) sequence of a Cellular Fibronectin and recognizes thus only the Cellular Fibronectin (cFN). Clone DHI has been shown to specifically block Chondrocyte condensation in Chicken embryos (ref. 5).

Réactivité croisée (Details): Species reactivity (tested):Human, Chicken, Rat, Rabbit and Guinea Pig.

Purification: Ig Fraction

Immunogène: Purified Fibronectin from A8387 fibrosarcoma cells (ref. 21). Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, 0.09 % (w/v) Sodium Azide, 1.0 % (w/v) BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur Fibronectin

Antigène: Fibronectin

Sujet: Fibronectins are diverse high molecular weight cell adhesion glycoproteins found in basement membranes, in the interstitial connective tissue matrix, and in soluble in plasma and other body fluids. In adult tissues most fibronectin is produced by hepatocytes (pFn) that differ from locally produced cellular fibronectins. A monoclonal antibody (AM32091PU-N Clone BF12) has been produced to fibronectin that reacts with both the cellular and plasma forms of the protein and recognizes the cell-binding region in fibronectin. The monoclonal antibody DH1 recognizes only cellular form of Fibronectin. DH1 is specific to the extra domain A (EDA) of the molecule. cFns are found in some basement membranes during development and only in distinct tissues in adult, for instance in smooth muscle and alveolar walls of airways. cFns are abundant in the plasma of carcinoma patients and in the stroma of various carcinomas.Synonyms: CIG, Cold-insoluble globulin, FN1

ID gène: 2335

NCBI Accession: NP_002017

UniProt: P02751